Please join a free live webinar with guest speaker Dr. József Kardos, which will be held on March 12, 2025 at 18:00 CET. The attendance at the approx 60 minutes long CD Spectroscopy for Experimental Investigation and Verification of Protein Structure in the AlphaFold Era webinar is free but registration is needed:
| R E G I S T E R |
We present a robust methodology for protein structure determination and highlight the crucial role of CD spectroscopy in validating bioinformatics predictions, using numerous examples of disease-related proteins. With desktop or cutting-edge plate reader CD devices, high-throughput experimental validation and protein structure screening become a reality. Moreover, BeStSel is now integrated into Spectra Manager 2.5 of JASCO’s new CD instruments, providing an advanced tool for industry and academia.
Dr. József Kardos has been leading the Neuroimmunology Research Group at the Department of Biochemistry, Eötvös Loránd University . His primary research interests include protein folding and misfolding, the structural and thermodynamic principles behind protein aggregation and amyloid formation, proteomics studies on the role of protein aggregation in neurodegeneration, immune complement system activation, and the complement system’s function in the brain. He has developed innovative methods to investigate the thermodynamics of amyloid formation and to analyze protein secondary structure and fold using CD spectroscopy. Together with his colleague Dr. András Micsonai, he developed the BeStSel method, which allows for the estimation of protein structure from CD spectra with superior accuracy.
